Carticel Plus is a dietary supplement used to help manage osteoarthritis in areas such as the knee, hip, spine, and hand. It can also be beneficial in conditions like rheumatoid arthritis, sports injuries, migraines, various skin disorders (such as psoriasis), vascular issues (like atherosclerosis), kidney stones, and inflammatory bowel conditions (e.g., ulcerative colitis and leaky gut syndrome).
(Use this medication only as advised by a registered physician.)
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Glucosamine, a naturally occurring amino sugar in the body and some foods is a foundational component in the synthesis of glycosaminoglycans (GAGs) like Hyaluronic Acid, Keratan Sulfate, and Chondroitin Sulfate. These GAGs bind with proteins to form proteoglycans, which are crucial for building articular cartilage. Osteoarthritis can develop when cartilage in a joint degenerates. Glucosamine also supports the development of tendons, ligaments, nails, and other connective tissues. Supplementing with Glucosamine Sulfate increases glucosamine levels, supporting cartilage repair and production. Additionally, it activates chondrocytes within the cartilage to produce GAGs and proteoglycans.
Chondroitin Sulfate, another GAG found in connective tissue, especially articular cartilage, provides material for proteoglycans. It protects healthy cartilage from deterioration by inhibiting the Matrix Metalloproteinase (MMP) enzyme, which breaks down proteoglycans.
Combining Glucosamine with Chondroitin Sulfate enhances efficacy, with data showing significant benefits in osteoarthritis cases, addressing symptoms and potentially slowing disease progression. This combination can prevent osteoarthritis in healthy adults and is as effective as NSAIDs for osteoarthritic pain with better tolerability. It also aids in repairing musculoskeletal soft tissue injuries, such as strains in tendons or ligaments.
(Use this medication only as advised by a registered physician.)
No significant interactions have been reported between Glucosamine and Chondroitin and other common drug categories like antibiotics, antidepressants, antihypertensives, nitrates, antiarrhythmics, anxiolytics, hypoglycemics, antisecretives, and anti-asthmatics. Chondroitin may enhance the blood-thinning effects of anticoagulants like Warfarin and Heparin.
No contraindications are known for Glucosamine and Chondroitin except in individuals with known hypersensitivity to shellfish or sulfur.
Studies indicate that Glucosamine and Chondroitin are generally safe and have no notable side effects. Mild, reversible gastrointestinal symptoms (such as flatulence) are rare and similar to placebo responses.
It is advised that women who are pregnant or may become pregnant avoid Glucosamine and Chondroitin supplementation due to insufficient research on their effects on a developing fetus. Use during pregnancy or lactation should only occur with medical advice and caution.
Diabetic patients should monitor blood glucose levels regularly when taking Glucosamine. No specific studies exist for those with renal or hepatic impairment, though the toxicological profile does not suggest limitations for these patients. However, patients with severe renal or hepatic insufficiency should use it under medical supervision. Glucosamine and Chondroitin are not recommended for children.
Store in a cool, dry place away from light.
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